Cat: PA2000-5314

Recombinant Human ABLIM3 Protein,His

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Analytical Data

  • Gene name

    ABLIM3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    abLIM-3; Ablim3; ABLM3_HUMAN; Actin binding LIM Protein 3; Actin binding LIM Protein family member 3

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O94929

  • Expression Region

    1-683aa

  • AA Sequence

    MNTSIPYQQN PYNPRGSSNV IQCYRCGDTC KGEVVRVHNN HFHIRCFTCQ VCGCGLAQSG FFFKNQEYIC TQDYQQLYGT RCDSCRDFIT GEVISALGRT YHPKCFVCSL CRKPFPIGDK VTFSGKECVC QTCSQSMASS KPIKIRGPSH CAGCKEEIKH GQSLLALDKQ WHVSCFKCQT CSVILTGEYI SKDGVPYCES DYHAQFGIKC ETCDRYISGR VLEAGGKHYH PTCARCVRCH QMFTEGEEMY LTGSEVWHPI CKQAARAEKK LKHRRTSETS ISPPGSSIGS PNRVICAKVD NEILNYKDLA ALPKVKSIYE VQRPDLISYE PHSRYMSDEM LERCGYGESL GTLSPYSQDI YENLDLRQRR ASSPGYIDSP TYSRQGMSPT FSRSPHHYYR SGPESGRSSP YHSQLDVRSS TPTSYQAPKH FHIPAGDSNI YRKPPIYKRH GDLSTATKSK TSEDISQTSK YSPIYSPDPY YASESEYWTY HGSPKVPRAR RFSSGGEEDD FDRSMHKLQS GIGRLILKEE MKARSSSYAD PWTPPRSSTS SREALHTAGY EMSLNGSPRS HYLADSDPLI SKSASLPAYR RNGLHRTPSA DLFHYDSMNA VNWGMREYKI YPYELLLVTT RGRNRLPKDV DRTRLERHLS QEEFYQVFGM TISEFDRLAL WKRNELKKQA RLF

  • Molecular Weight

    77.8 KDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ABLIM3 (Actin-Binding LIM Protein 3) is an important member of the LIM-domain protein family, known for its pivotal role in regulating actin cytoskeleton dynamics and cellular processes such as proliferation, differentiation, and migration. Research into ABLIM3 has gained momentum due to its implications in various diseases, particularly in cancer where it may influence tumor progression and metastasis. The protein is characterized by its multiple LIM domains, which facilitate interactions with various signaling pathways and cytoskeletal components. The study of ABLIM3 recombinant protein is crucial for elucidating its functional mechanisms and molecular interactions. By generating recombinant ABLIM3, researchers can investigate its binding properties, post-translational modifications, and role in cellular signaling. Additionally, understanding the structure and function of ABLIM3 can provide insights into its potential as a therapeutic target. Given its involvement in critical cellular functions, ABLIM3 represents a valuable focal point for studying the molecular underpinnings of both normal physiology and pathological conditions, underscoring the necessity for advanced research in this area.

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