Analytical Data
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基因名
NUDT22
- Application
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别名
MGC13045; Nucleoside diphosphate-linked moiety X motif 22; NUD22_HUMAN; Nudix (nucleoside diphosphate linked moiety X) type motif 22; Nudix motif 22; NUDT22
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BRQ3
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表达区间
1-303 aa
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氨基酸序列
MDPEVTLLLQ CPGGGLPQEQ IQAELSPAHD RRPLPGGDEA ITAIWETRLK AQPWLFDAPK FRLHSATLAP IGSRGPQLLL RLGLTSYRDF LGTNWSSSAA WLRQQGATDW GDTQAYLADP LGVGAALATA DDFLVFLRRS RQVAEAPGLV DVPGGHPEPQ ALCPGGSPQH QDLAGQLVVH ELFSSVLQEI CDEVNLPLLT LSQPLLLGIA RNETSAGRAS AEFYVQCSLT SEQVRKHYLS GGPEAHESTG IFFVETQNVQ RLLETEMWAE LCPSAKGAII LYNRVQGSPT GAALGSPALL PPL
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分子量
32.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NUDT22 is a member of the Nudix hydrolase family, which is known for its role in the hydrolysis of nucleoside diphosphates and other nucleotide derivatives. The study of NUDT22 has gained significance due to its potential involvement in various cellular processes, including RNA metabolism, stress response, and the regulation of nucleotide pools. Aberrant expression or mutations in NUDT22 have been linked to several diseases, including cancer, where its function in maintaining nucleotide homeostasis may influence tumorigenesis. Recent research has focused on understanding the mechanistic pathways through which NUDT22 exerts its effects, aiming to elucidate its substrates and interactions within cellular contexts. This protein's ability to modulate the levels of substrates like ADP-ribose suggests its relevance in cellular signaling and stress response pathways. Moreover, insights gained from NUDT22 studies could pave the way for novel therapeutic strategies targeting nucleotide metabolism in disease states. Overall, the investigation of NUDT22 is a promising avenue within molecular biology and therapeutic research, with implications for understanding fundamental biological processes and potential clinical applications.
