Analytical Data
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Gene name
NUDT22
- Application
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Alternative Names
MGC13045; Nucleoside diphosphate-linked moiety X motif 22; NUD22_HUMAN; Nudix (nucleoside diphosphate linked moiety X) type motif 22; Nudix motif 22; NUDT22
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BRQ3
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Expression Region
1-303 aa
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AA Sequence
MDPEVTLLLQ CPGGGLPQEQ IQAELSPAHD RRPLPGGDEA ITAIWETRLK AQPWLFDAPK FRLHSATLAP IGSRGPQLLL RLGLTSYRDF LGTNWSSSAA WLRQQGATDW GDTQAYLADP LGVGAALATA DDFLVFLRRS RQVAEAPGLV DVPGGHPEPQ ALCPGGSPQH QDLAGQLVVH ELFSSVLQEI CDEVNLPLLT LSQPLLLGIA RNETSAGRAS AEFYVQCSLT SEQVRKHYLS GGPEAHESTG IFFVETQNVQ RLLETEMWAE LCPSAKGAII LYNRVQGSPT GAALGSPALL PPL
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Molecular Weight
32.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NUDT22 is a member of the Nudix hydrolase family, which is known for its role in the hydrolysis of nucleoside diphosphates and other nucleotide derivatives. The study of NUDT22 has gained significance due to its potential involvement in various cellular processes, including RNA metabolism, stress response, and the regulation of nucleotide pools. Aberrant expression or mutations in NUDT22 have been linked to several diseases, including cancer, where its function in maintaining nucleotide homeostasis may influence tumorigenesis. Recent research has focused on understanding the mechanistic pathways through which NUDT22 exerts its effects, aiming to elucidate its substrates and interactions within cellular contexts. This protein's ability to modulate the levels of substrates like ADP-ribose suggests its relevance in cellular signaling and stress response pathways. Moreover, insights gained from NUDT22 studies could pave the way for novel therapeutic strategies targeting nucleotide metabolism in disease states. Overall, the investigation of NUDT22 is a promising avenue within molecular biology and therapeutic research, with implications for understanding fundamental biological processes and potential clinical applications.
