Cat: PA2000-5306

Recombinant Human ABHD14A Protein,His

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Analytical Data

  • Gene name

    ABHD14A

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ABHD14A; UNQ1913/PRO4373; Protein ABHD14A

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9BUJ0

  • Expression Region

    1-271aa

  • AA Sequence

    MVGALCGCWFRLGGARPLIPLGPTVVQTSMSRSQVALLGLSLLLMLLLYVGLPGPPEQTSCLWGDPNVTVLAGLTPGNSPIFYREVLPLNQAHRVEVVLLHGKAFNSHTWEQLGTLQLLSQRGYRAVALDLPGFGNSAPSKEASTEAGRAALLERALRDLEVQNAVLVSPSLSGHYALPFLMRGHHQLHGFVPIAPTSTQNYTQEQFWAVKTPTLILYGELDHILARESLRQLRHLPNHSVVKLRNAGHACYLHKPQDFHLVLLAFLDHLP

  • Molecular Weight

    29.7 KDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ABHD14A, a member of the serine hydrolase family, has gained significant attention in recent years due to its potential role in lipid metabolism and cellular signaling pathways. It is predominantly expressed in the brain and has been implicated in various physiological processes, including neurotransmitter regulation and the maintenance of neuronal integrity. Research indicates that ABHD14A may be involved in the hydrolysis of endocannabinoids, which are crucial for modulating synaptic transmission and neuroplasticity. Dysregulation of ABHD14A has been associated with several neurological disorders, making it a potential target for therapeutic interventions. The production of recombinant ABHD14A protein enables detailed structural and functional studies, facilitating the elucidation of its enzymatic mechanisms and interactions with lipid substrates. Understanding the biochemical properties and biological functions of ABHD14A could provide valuable insights into its role in health and disease, paving the way for novel treatment strategies in neurodegenerative and psychiatric disorders.

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