Analytical Data
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Gene name
NUDT13
- Application
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Alternative Names
NUDT13; Nucleoside diphosphate-linked moiety X motif 13; Nudix motif 13; EC 3.-.-.-; Protein KiSS-16
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86X67
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Expression Region
1-352 aa
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AA Sequence
MSLYCGIACR RKFFWCYRLL STYVTKTRYL FELKEDDDAC KKAQQTGAFY LFHSLAPLLQ TSAHQYLAPR HSLLELERLL GKFGQDAQRI EDSVLIGCSE QQEAWFALDL GLDSSFSISA SLHKPEMETE LKGSFIELRK ALFQLNARDA SLLSTAQALL RWHDAHQFCS RSGQPTKKNV AGSKRVCPSN NIIYYPQMAP VAITLVSDGT RCLLARQSSF PKGMYSALAG FCDIGESVEE TIRREVAEEV GLEVESLQYY ASQHWPFPSG SLMIACHATV KPGQTEIQVN LRELETAAWF SHDEVATALK RKGPYTQQQN GTFPFWLPPK LAISHQLIKE WVEKQTCSSL PA
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Molecular Weight
39.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NUDT13, a member of the Nudix hydrolase family, has garnered attention due to its potential role in cellular metabolism and stress response. This enzyme is known to hydrolyze various nucleotides and is believed to play a critical role in the regulation of nucleotide levels within the cell, which is essential for maintaining cellular homeostasis. Dysregulation of NUDT13 has been implicated in several diseases, including cancer and neurodegenerative disorders, suggesting that understanding its biological functions could provide insights into therapeutic targets. Recent studies have focused on the structural characterization and enzymatic mechanisms of NUDT13 to elucidate how it interacts with different substrates. Additionally, the recombinant expression of NUDT13 allows for detailed analysis of its activity and potential inhibitors, offering a pathway for drug discovery and development. The ongoing research into the functional implications of NUDT13 underscores its significance in molecular biology and potential contributions to developing strategies for disease intervention. Overall, as a key player in nucleotide metabolism, NUDT13 represents a promising target for further investigation in both basic and applied scientific research.
