Analytical Data
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Gene name
NSFL1C
- Application
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Alternative Names
DJ776F14.1; MGC3347; NSF1C_HUMAN; NSFL1 (p97) cofactor (p47); NSFL1 cofactor p47; NSFL1C; OTTHUMP00000029972; OTTHUMP00000029974; p47; P47 protein ; p97 cofactor p47; SHP1 homolog ; UBX domain protein 2C ; UBX domain-containing protein 2C; UBX1; UBXD10; UBXN2C
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UNZ2
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Expression Region
1-370 aa
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AA Sequence
MAAERQEALR EFVAVTGAEE DRARFFLESA GWDLQIALAS FYEDGGDEDI VTISQATPSS VSRGTAPSDN RVTSFRDLIH DQDEDEEEEE GQRFYAGGSE RSGQQIVGPP RKKSPNELVD DLFKGAKEHG AVAVERVTKS PGETSKPRPF AGGGYRLGAA PEEESAYVAG EKRQHSSQDV HVVLKLWKSG FSLDNGELRS YQDPSNAQFL ESIRRGEVPA ELRRLAHGGQ VNLDMEDHRD EDFVKPKGAF KAFTGEGQKL GSTAPQVLST SSPAQQAENE AKASSSILID ESEPTTNIQI RLADGGRLVQ KFNHSHRISD IRLFIVDARP AMAATSFILM TTFPNKELAD ESQTLKEANL LNAVIVQRLT
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Molecular Weight
40.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NSFL1C, also known as p47, is a vital protein involved in the regulation of the endoplasmic reticulum (ER) and Golgi apparatus homeostasis. It plays a crucial role in various cellular processes, including protein trafficking and degradation. Research has shown that NSFL1C is part of the NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor (SNARE) complex, which is essential for intracellular membrane fusion events. Dysfunction of NSFL1C has been linked to several diseases, including neurodegenerative disorders and cancer, making it an important target for therapeutic interventions. The study of recombinant NSFL1C protein allows for a deeper understanding of its structure-function relationships and interactions with other cellular components. By expressing and purifying this protein, researchers can explore its biochemical properties and cellular roles, paving the way for potential applications in drug development and disease treatment. Additionally, insights gained from NSFL1C research may lead to novel strategies to manipulate intracellular trafficking pathways, enhancing our understanding of cell biology and its implications in health and disease.
