Analytical Data
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Gene name
SERTAD1
- Application
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Alternative Names
SERTAD1;SEI1;TRIPBR1;SERTA domain-containing Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UHV2
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Expression Region
1-236aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMLSKGL KRKREEEEEK EPLAVDSWWL DPGHTAVAQA PPAVASSSLF DLSVLKLHHS LQQSEPDLRH LVLVVNTLRR IQASMAPAAA LPPVPSPPAA PSVADNLLAS SDAALSASMA SLLEDLSHIE GLSQAPQPLA DEGPPGRSIG GAAPSLGALD LLGPATGCLL DDGLEGLFED IDTSMYDNEL WAPASEGLKP GPEDGPGKEE APELDEAELD YLMDVLVGTQ ALERPPGPGR
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Molecular Weight
27 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SERTAD1, or SERTA domain containing protein 1, is a member of the SERTAD family, which plays a pivotal role in various biological processes, including cell proliferation, differentiation, and tumorigenesis. This protein contains a unique SERTA domain, which is implicated in the modulation of transcriptional activities and protein interactions, particularly in the context of cancer biology. Recent studies have highlighted SERTAD1 as a potential regulator of key oncogenic pathways, making it a point of interest in cancer research. Its expression levels have been correlated with the progression of several malignancies, indicating that it may serve as a biomarker for cancer diagnosis and prognosis. Moreover, SERTAD1 has been shown to interact with critical proteins in transcriptional regulation, including p53 and β-catenin, thereby influencing cell cycle dynamics and apoptosis. The exploration of SERTAD1 as a recombinant protein offers insights into its functional mechanisms and biological roles, providing a valuable tool for understanding its contributions to tumorigenesis. Research focused on SERTAD1 could pave the way for novel therapeutic strategies targeting its pathways, enhancing the potential for cancer treatment and management. Thus, the study of SERTAD1 recombinant protein not only furthers our comprehension of cellular mechanisms but also holds promise for translational applications in oncology.
