Analytical Data
-
基因名
AP2b1
- Application
-
别名
AP2b1；ADTB2；CLAPB1；AP-2 complex subunit beta
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q10567
-
表达区间
1-584aa
-
氨基酸序列
MTDSKYFTTTKKGEIFELKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIVQKRPEILKHEMKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVAAKEVVLAEKPLISEETDLIEPTLLDELICYIGTLASVYHKPPSAFVEG
-
分子量
73.3 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AP2b1, a member of the adaptor protein complex family, plays a crucial role in clathrin-mediated endocytosis, which is essential for cellular transport and signaling processes. This protein facilitates the internalization of membrane proteins and regulates various cellular activities by linking membrane proteins to the clathrin coat, enabling the formation of vesicles that transport cargo to different cellular compartments. Research on AP2b1 has gained momentum due to its implications in several physiological and pathological processes; abnormalities in its function can lead to diseases such as cancer and neurological disorders. As a result, the development of recombinant AP2b1 proteins has become a focus of study, aiming to better understand its structure-function relationship and mechanisms of action. By producing AP2b1 in a recombinant form, researchers can investigate its interactions with other proteins, elucidate its role in endocytic trafficking, and explore its potential as a therapeutic target. The study of AP2b1 not only enhances our understanding of cellular dynamics but also opens avenues for novel approaches in drug development and biomarker discovery for diseases linked to endocytic dysregulation. Thus, the investigation of recombinant AP2b1 proteins holds significant promise for advancing both basic science and translational research in cellular biology and medicine.
