Analytical Data
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基因名
SEC13
- Application
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别名
SEC13;D3S1231E;SEC13A;SEC13L1;Protein SEC13 homolog
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55735
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表达区间
1-322aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSHMVSVINTVDT SHEDMIHDAQ MDYYGTRLAT CSSDRSVKIF DVRNGGQILI ADLRGHEGPV WQVAWAHPMY GNILASCSYD RKVIIWREEN GTWEKSHEHA GHDSSVNSVC WAPHDYGLIL ACGSSDGAIS LLTYTGEGQW EVKKINNAHT IGCNAVSWAPAVVPGSLIDH PSGQKPNYIK RFASGGCDNL IKLWKEEEDG QWKEEQKLEA HSDWVRDVAW APSIGLPTST IASCSQDGRV FIWTCDDASS NTWSPKLLHK FNDVVWHVSW SITANILAVS GGDNKVTLWK ESVDGQWVCI SDVNKGQGSV SASVTEGQQN EQ
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分子量
38 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SEC13 is a crucial protein that plays a significant role in vesicle transport and protein secretion within eukaryotic cells. It is a component of the coat protein complex II (COPII), which facilitates the budding of transport vesicles from the endoplasmic reticulum (ER) to the Golgi apparatus. The study of SEC13 has garnered interest due to its involvement in various cellular processes, including the maintenance of cellular architecture and regulation of protein trafficking. Abnormalities in SEC13 function have been linked to several diseases, including neurodegenerative disorders and certain types of cancer, highlighting its importance in cellular homeostasis. Furthermore, SEC13's structural features and interactions with other COPII components provide insights into the mechanisms of vesicle formation and cargo selection. Research on SEC13 not only aims to elucidate its fundamental biological roles but also explores potential therapeutic targets for conditions arising from its dysfunction. As scientists continue to investigate SEC13's diverse functions and regulatory pathways, a deeper understanding of this protein could significantly advance the field of cell biology and contribute to the development of innovative treatments for related diseases.
