Analytical Data
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Gene name
SDR16C5
- Application
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Alternative Names
SDR16C5;RDHE2;Epidermal retinol dehydrogenase 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N3Y7
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Expression Region
32-269aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSPKPRKNV AGEIVLITGA GSGLGRLLAL QFARLGSVLV LWDINKEGNE ETCKMAREAG ATRVHAYTCD CSQKEGVYRV ADQVKKEVGD VSILINNAGI VTGKKFLDCP DELMEKSFDV NFKAHLWTYK AFLPAMIAND HGHLVCISSS AGLSGVNGLA DYCASKFAAF GFAESVFVET FVQKQKGIKT TIVCPFFIKT GMFEGCTTGC PSLLPILEPK YAVEKIVEAI LQEKMYLYMP K
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Molecular Weight
28 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The SDR16C5 protein, also known as Short-Chain Dehydrogenase/Reductase 16C5, has garnered attention in recent years due to its potential roles in various biological processes and its association with certain diseases. As a member of the SDR family, SDR16C5 is involved in the metabolism of steroid hormones and fatty acids, suggesting its importance in both endocrine and metabolic regulation. Research has indicated that SDR16C5 may play a critical role in mediating cellular responses to oxidative stress and could be implicated in the pathogenesis of conditions like diabetes and cardiovascular diseases. Furthermore, its expression levels have been found to vary across different tissues, hinting at tissue-specific functions that warrant further investigation. Advances in molecular biology techniques have enabled researchers to dissect the biochemical characteristics and regulatory mechanisms of SDR16C5, leading to insights into its enzymatic activity and interactions with various substrates. Understanding SDR16C5's structure and functionality could pave the way for developing novel therapeutic strategies targeting this protein, particularly in the context of metabolic disorders. Additionally, recent studies have begun to explore the protein’s involvement in cancer biology, where it may influence tumor growth and progression. Overall, the SDR16C5 protein holds significant promise as a biomarker and therapeutic target, making it an important focus for ongoing research in the fields of biochemistry and molecular medicine.
