Analytical Data
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基因名
NOL5A
- Application
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别名
Nucleolar protein 56. Nucleolar protein 5A
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00567
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表达区间
1-174 aa
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氨基酸序列
MKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQED
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分子量
45.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NOL5A, a member of the nucleolar family of RNA-binding proteins, has garnered significant interest in recent years due to its potential roles in cell proliferation, differentiation, and stress response. This protein is primarily located in the nucleolus, where it is involved in ribosome biogenesis and pre-rRNA processing. Dysregulation of NOL5A has been associated with various cancers, making it a candidate for further study in oncological research. Its ability to interact with multiple RNA molecules suggests it may play a crucial role in post-transcriptional regulation and cellular homeostasis. Recent advancements in protein expression and purification techniques have facilitated the development of recombinant NOL5A for functional assays and structural studies, providing insights into its mechanisms of action. Understanding the structural and functional properties of NOL5A could unveil novel therapeutic targets and strategies for cancer treatment. This research not only aims to elucidate the biological significance of NOL5A but also explores its potential as a biomarker for disease progression or response to therapy, emphasizing its relevance in contemporary biomedical research.
