Analytical Data
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Gene name
NME7
- Application
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Alternative Names
MN23H7; NDK 7; NDK7_HUMAN; NDP kinase 7; nm23 H7 ; nm23-H7; NME/NM23 family member 7; Nme7; Non metastatic cells 7 protein expressed in (nucleoside diphosphate kinase); Nucleoside diphosphate kinase 7
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y5B8
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Expression Region
1-376 aa
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AA Sequence
MNHSERFVFI AEWYDPNASL LRRYELLFYP GDGSVEMHDV KNHRTFLKRT KYDNLHLEDL FIGNKVNVFS RQLVLIDYGD QYTARQLGSR KEKTLALIKP DAISKAGEII EIINKAGFTI TKLKMMMLSR KEALDFHVDH QSRPFFNELI QFITTGPIIA MEILRDDAIC EWKRLLGPAN SGVARTDASE SIRALFGTDG IRNAAHGPDS FASAAREMEL FFPSSGGCGP ANTAKFTNCT CCIVKPHAVS EGLLGKILMA IRDAGFEISA MQMFNMDRVN VEEFYEVYKG VVTEYHDMVT EMYSGPCVAM EIQQNNATKT FREFCGPADP EIARHLRPGT LRAIFGKTKI QNAVHCTDLP EDGLLEVQYF FKILDN
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Molecular Weight
42.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NME7, a member of the NME (NME/NM23) family of genes, has emerged as a subject of interest in cancer research due to its potential roles in tumor progression and metastasis. Initially identified for its involvement in the regulation of cellular processes, NME7 is thought to play a crucial role in various biological functions, including cell signaling, proliferation, and apoptosis. Recent studies have suggested that alterations in the expression levels of NME7 may correlate with unfavorable patient outcomes in different cancer types. Its resemblances to other NME family proteins, known for their nucleoside diphosphate kinase activity and involvement in the modulation of cellular energy homeostasis and metastasis, further underline the need for a comprehensive understanding of NME7’s mechanisms of action. Research into its recombinantly expressed protein could provide insights into its structure-function relationship and interactions with other cellular components, paving the way for developing targeted therapeutic strategies. By utilizing advanced techniques in protein engineering and characterization, scientists aim to decode the intricacies of NME7’s function, potentially linking it to novel therapeutic applications in oncology. Such investigations are critical for unveiling the broader implications of NME7 in cancer biology and for establishing its role as a potential biomarker for diagnosis or prognosis.
