Cat: PA1000-2737

Recombinant Human RND3 Protein,His

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Analytical Data

  • 基因名

    RND3

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    RND3;ARHE;RHO8;RHOE;Rho-related GTP-binding Protein RhoE

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P61587

  • 表达区间

    1-241aa

  • 氨基酸序列

    MGSSHHHHHHSSGLVPRGSHMKERRASQKLSSKSIMDPNQNVKCKIVVVG DSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSG SPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKM LLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVA TDLRKDKAKSC

  • 分子量

    29 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RND3, also known as Rho family GTPase 3, is a member of the Rho family of small GTPases that play crucial roles in various cellular processes, including cytoskeletal dynamics, cell migration, and proliferation. Research has shown that RND3 is involved in both physiological and pathological contexts, such as cancer progression and neuronal development. Unlike other Rho GTPases that primarily function as molecular switches controlling cellular signaling, RND3 exhibits unique properties, including a lack of GTP binding ability, which suggests that it may regulate signaling pathways differently. The study of recombinant RND3 proteins aims to uncover their specific functions and interactions at a molecular level, particularly in the context of disease mechanisms. Utilizing recombinant techniques allows researchers to produce RND3 in a controlled environment, facilitating the investigation of its structural characteristics and functional implications. Understanding RND3's role in cellular processes is essential for determining its potential as a therapeutic target in disorders where its dysregulation is implicated. The exploration of RND3's interactions with other proteins and its upstream and downstream signaling pathways could also provide insights into novel treatment strategies for various diseases. Thus, the research on RND3 recombinant proteins is pivotal to elucidating the complex biological functions of this GTPase and fostering the development of targeted interventions in related medical fields.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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