Cat: PA2000-9643

Recombinant Human NDUFAB1 Protein,His

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Analytical Data

  • 基因名

    NDUFAB1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    ACP; ACPM_HUMAN; Acyl carrier protein; Acyl carrier protein mitochondrial; CI SDAP; CI-SDAP; FASN 2A; FASN2A; MGC65095; Mitochondrial acyl carrier protein; mitochondrial; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 8kDa; NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1; NADH ubiquinone oxidoreductase 9.6 kDa subunit; NADH ubiquinone oxidoreductase SDAP subunit; NADH-ubiquinone oxidoreductase 9.6 kDa subunit; NDUFAB 1; ndufab1; SDAP

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O14561

  • 表达区间

    69-156 aa

  • 氨基酸序列

    SD MPPLTLEGIQ DRVLYVLKLY DKIDPEKLSV NSHFMKDLGL DSLDQVEIIM AMEDEFGFEI PDIDAEKLMC PQEIVDYIAD KKDVYE

  • 分子量

    17.4 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

NDUFAB1 (NADH:ubiquinone oxidoreductase complex assembly factor 1) is a crucial protein involved in the assembly and stabilization of the mitochondrial respiratory chain complex I. This complex is essential for cellular respiration as it plays a vital role in the electron transport chain, facilitating ATP production by transferring electrons from NADH to ubiquinone. Mutations in the NDUFAB1 gene have been associated with various mitochondrial disorders, leading to impaired energy metabolism and a range of clinical manifestations. Research on NDUFAB1 recombinant protein has gained significance due to its potential implications in understanding mitochondrial diseases and developing therapeutic strategies. By studying the structure and function of NDUFAB1, scientists aim to elucidate its role in complex I assembly and function, potentially identifying key molecular mechanisms that could be targeted for intervention in mitochondrial dysfunction. Advances in recombinant protein technology enable the production and characterization of NDUFAB1, allowing for detailed investigations into its interactions with other mitochondrial components and its impact on cellular respiration. As ongoing studies seek to uncover the precise biochemical pathways and regulatory networks involving NDUFAB1, this research holds promise for enhancing our understanding of mitochondrial biology and the development of innovative treatments for related disorders. The insights gained from NDUFAB1 studies could pave the way for novel therapeutic approaches, particularly for patients suffering from mitochondrial diseases, thereby highlighting the relevance of this research in both basic science and clinical applications.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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