Analytical Data
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基因名
RLN2
- Application
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别名
RLN2;Prorelaxin H2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P04090
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表达区间
25-185aa
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氨基酸序列
MGSSHHHHHHMGSSHHHHHHSSGLVPRGSHMGSDSWMEEVIKLCGRELVR AQIAICGMSTWSKRSLSQEDAPQTPRPVAEIVPSFINKDTETINMMSEFV ANLPQELKLTLSEMQPALPQLQQHVPVLKDSSLLFEEFKKLIRNRQSEAA DSSPSELKYLGLDTHSRKKRQLYSALANKCCHVGCTKRSLARFC
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分子量
21 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Recombinant RLN2 (Relaxin 2) is a peptide hormone that belongs to the relaxin family, playing a crucial role in various physiological processes, including reproductive functions and cardiovascular regulation. Historically, research on RLN2 has focused on its involvement in pregnancy, where it is produced by the corpus luteum and is thought to facilitate uterine remodeling, cervical softening, and angiogenesis. Beyond its reproductive implications, emerging studies have revealed that RLN2 may exhibit therapeutic potential in the treatment of various cardiovascular diseases by promoting vasodilation and inhibiting fibrosis. Additionally, RLN2 is being explored for its roles in metabolic regulation, neuroprotection, and modulating inflammation, making it a target of interest in multiple biomedical research areas. The advent of recombinant technology allows for the efficient production of RLN2, enabling further exploration of its molecular mechanisms, signaling pathways, and therapeutic applications. Current studies are investigating the optimal delivery methods and formulations of RLN2 to maximize its biological activity and therapeutic effectiveness. As our understanding of RLN2 expands, it holds promise for innovative treatments for conditions such as heart failure, diabetes, and other disorders linked to its regulatory functions.












