Analytical Data
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基因名
NDNL2
- Application
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别名
NSMCE3; HCA4; MAGEG1; NDNL2; Non-structural maintenance of chromosomes element 3 homolog; Non-SMC element 3 homolog; Hepatocellular carcinoma-associated protein 4; MAGE-G1 antigen; Melanoma-associated antigen G1; Necdin-like protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96MG7
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表达区间
1-304 aa
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氨基酸序列
MLQKPRNRGR SGGQAERDRD WSHSGNPGAS RAGEDARVLR DGFAEEAPST SRGPGGSQGS QGPSPQGARR AQAAPAVGPR SQKQLELKVS ELVQFLLIKD QKKIPIKRAD ILKHVIGDYK DIFPDLFKRA AERLQYVFGY KLVELEPKSN TYILINTLEP VEEDAEMRGD QGTPTTGLLM IVLGLIFMKG NTIKETEAWD FLRRLGVYPT KKHLIFGDPK KLITEDFVRQ RYLEYRRIPH TDPVDYEFQW GPRTNLETSK MKVLKFVAKV HNQDPKDWPA QYCEALADEE NRARPQPSGP APSS
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分子量
34.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NDNL2, a member of the neurodegeneration-associated protein family, has gained significant attention in recent years due to its potential implications in various neurodegenerative diseases. Research has indicated that NDNL2 may play a crucial role in neuronal survival, synaptic function, and the modulation of cellular stress responses. The protein's involvement in processes such as autophagy and apoptosis highlights its importance in maintaining cellular homeostasis within the nervous system. In the context of diseases like Alzheimer's and Parkinson's, aberrations in NDNL2 expression and function have been linked to the progression of neurodegeneration. The recombinant expression and characterization of NDNL2 provide crucial insights into its structure-function relationships and biological activities, paving the way for potential therapeutic strategies targeting neuroprotective pathways. Given the increasing prevalence of neurodegenerative disorders in aging populations, understanding the function of NDNL2 and its interactions with other cellular components could offer novel approaches for treatment and prevention. Thus, investigating NDNL2 as a recombinant protein not only facilitates a deeper understanding of its molecular mechanisms but also emphasizes its relevance in the fight against neurodegenerative diseases.
