Analytical Data
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基因名
aMSH
- Application
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别名
aMSH;AMSHLP;KIAA1373;AMSH-like protease
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95630
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表达区间
1-424aa
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氨基酸序列
MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIY SEEGNIEHAFILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAF PKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVA QQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDL EKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPGALSNSESIPT IDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLH THCSYQMMLPESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSK DPPLFCSCSHVTVVDRAVTITDLR
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分子量
54 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Alpha-melanocyte-stimulating hormone (aMSH) is a peptide that plays a crucial role in the regulation of various physiological functions, including pigmentation, appetite control, and inflammatory responses. Research on aMSH has gained attention due to its potential therapeutic applications, particularly in the fields of obesity, skin disorders, and autoimmune diseases. The production of recombinant aMSH has become a focal point in biomedical research, as it allows for the generation of large quantities of the peptide for both experimental and clinical use. Utilizing techniques such as recombinant DNA technology and protein expression systems, researchers can produce aMSH in a cost-effective and efficient manner. The exploration of aMSH's mechanisms of action at the molecular and cellular levels has revealed insights into its interactions with melanocortin receptors, paving the way for novel drug development. Furthermore, studies investigating the role of aMSH in neuroinflammation and neuroprotection have opened new avenues for treating neurological disorders. Overall, the ongoing research into recombinant aMSH not only enhances our understanding of its biological significance but also holds promise for innovative therapeutic strategies targeting a range of health conditions.












