Analytical Data
-
Gene name
RCVRN
- Application
-
Alternative Names
RCVRN;RCV1;Recoverin
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P35243
-
Expression Region
1-200aa
-
AA Sequence
MGNSKSGALS KEILEELQLN TKFSEEELCS WYQSFLKDCP TGRITQQQFQ SIYAKFFPDT DPKAYAQHVF RSFDSNLDGT LDFKEYVIAL HMTTAGKTNQ KLEWAFSLYD VDGNGTISKN EVLEIVMAIF KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANK EILRLIQFEP QKVKEKMKNA
-
Molecular Weight
23 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RCVRN (Retinal Cone-specific Vision-related Protein) is a crucial protein implicated in the maintenance and function of photoreceptor cells, particularly in the retina where it plays a vital role in vision. Research on RCVRN has gained prominence due to its potential association with various retinal degenerative diseases, such as retinitis pigmentosa and age-related macular degeneration. Understanding the structure and function of RCVRN is essential for unraveling the molecular mechanisms underlying these conditions and for developing therapeutic strategies. Studies have shown that RCVRN is specifically expressed in cone photoreceptors, highlighting its significance in color vision. Additionally, the exploration of RCVRN as a target for gene therapy and regenerative medicine offers promising avenues for restoring vision in affected individuals. As scientists delve deeper into the biochemical pathways involving RCVRN, significant insights into the pathology of retinal diseases are anticipated, paving the way for innovative approaches in ocular therapeutics. Enhanced knowledge of RCVRN's role could thus not only contribute to basic science but can also impact clinical strategies aimed at combating vision loss.
