Cat: PA2000-1054

Recombinant Human NUSAP1 Protein,His

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Analytical Data

  • Gene name

    NUSAP1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    NUSAP1;ANKT;Nucleolar and spindle-associated Protein 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9BXS6

  • Expression Region

    1-441aa

  • AA Sequence

    MIIPSLEELD SLKYSDLQNL AKSLGLRANL RATKLLKALK GYIKHEARKG NENQDESQTS ASSCDETEIQ ISNQEEAERQ PLGHVTKTRR RCKTVRVDPD SQQNHSEIKI SNPTEFQNHE KQESQDLRAT AKVPSPPDEH QEAENAVSSG NRDSKVPSEG KKSLYTDESS KPGKNKRTAI TTPNFKKLHE AHFKEMESID QYIERKKKHF EEHNSMNELK QQPINKGGVR TPVPPRGRLS VASTPISQRR SQGRSCGPAS QSTLGLKGSL KRSAISAAKT GVRFSAATKD NEHKRSLTKT PARKSAHVTV SGGTPKGEAV LGTHKLKTIT GNSAAVITPF KLTTEATQTP VSNKKPVFDL KASLSRPLNY EPHKGKLKPW GQSKENNYLN QHVNRINFYK KTYKQPHLQT KEEQRKKREQ ERKEKKAKVL GMRRGLILAE D

  • Molecular Weight

    49.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

NUSAP1 (Nuclear and Spindle Associated Protein 1) is a protein that plays a critical role in cell division and the regulation of mitotic processes. Its expression is closely linked to various cellular functions, including the maintenance of genomic stability, microtubule organization, and chromosome segregation. Research has shown that NUSAP1 is significantly overexpressed in several types of cancer, suggesting that it may serve as a potential biomarker for tumor progression and a target for therapeutic intervention. The study of NUSAP1 recombinant proteins is pivotal for understanding the functional mechanisms underlying its role in mitosis and its implications in cancer biology. By producing and characterizing recombinant NUSAP1, scientists aim to elucidate its structural properties, interaction with other cellular components, and its potential as a therapeutic target. Furthermore, the investigation into NUSAP1 can provide insights into its regulatory pathways and how aberrations in its function may contribute to oncogenesis. Overall, the research surrounding NUSAP1 highlights its significance in cellular dynamics and its promise in cancer research, underscoring the need for further studies on this protein to explore its clinical utility.

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