Cat: PA2000-1036

Recombinant Human IFNa16 Protein,His

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Analytical Data

  • Gene name

    IFNa16

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    IFNa16;Interferon alpha-16

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P05015

  • Expression Region

    24-189aa

  • AA Sequence

    CDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFGFPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLEACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTNLQKGLRRKD

  • Molecular Weight

    23.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Interferon alpha 16 (IFNa16) is a type of cytokine that plays a vital role in the immune response against viral infections and has potential therapeutic applications in cancer treatment. Unlike other interferons, IFNa16 has unique properties that may enhance its effectiveness in modulating immune responses. Research has shown that IFNa16 can activate various immune cells, including natural killer (NK) cells and T cells, leading to increased antiviral activity and antitumor effects. The production of recombinant IFNa16 has gained attention due to its potential to serve as a more effective treatment option for diseases where traditional therapies have limitations. Investigations into the mechanistic pathways influenced by IFNa16 are critical for understanding its role in immune modulation and determining how it can be best utilized in clinical settings. With advancements in biotechnology, the ability to produce IFNa16 in recombinant forms has opened new avenues for therapeutic development, making it a subject of significant interest in both immunology and oncology research. Researchers aim to elucidate the specific pathways mediated by IFNa16, explore its interactions with other cytokines, and evaluate its safety and efficacy in various disease models. The ultimate goal is to harness the potential of IFNa16 to develop novel immunotherapies that can improve patient outcomes in viral infections and cancer.

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