Cat: PA1000-2629

Recombinant Human RAB3IL Protein,His

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Analytical Data

  • Gene name

    RAB3IL

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    RAB3IL1;Guanine nucleotide exchange factor for Rab-3A

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8TBN0

  • Expression Region

    1-382aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMWSGPPQ PDQGLPPPLA AVPVPWKSTD PCQGHRESPG ALVETSAGEE AQGQEGPAAA QLDVLRLRSS SMEIREKGSE FLKEELHRAQ KELKLKDEEC ERLSKVREQL EQELEELTAS LFEEAHKMVR EANMKQAASE KQLKEARGKI DMLQAEVTAL KTLVITSTPA SPNRELHPQL LSPTKAGPRK GHSRHKSTSS TLCPAVCPAA GHTLTPDREG KEVDTILFAE FQAWRESPTL DKTCPFLERV YREDVGPCLD FTMQELSVLV RAAVEDNTLT IEPVASQTLP TVKVAEVDCS STNTCALSGL TRTCRHRIRL GDSKSHYYIS PSSRARITAV CNFFTYIRYI QQGLVRQDAE PMFWEIMRLR KEMSLAKLGF FPQEA

  • Molecular Weight

    45 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RAB3IL is a member of the RAB GTPase family, which plays a crucial role in various cellular processes, including vesicle trafficking, neurotransmitter release, and neurotransmitter recycling. The study of RAB3IL has gained significance due to its potential implications in neural development and synaptic function. Recent research has shown that RAB3IL is involved in regulating the trafficking and positioning of synaptic vesicles, thereby influencing neurotransmitter release and synaptic plasticity. Its dysregulation has been associated with several neurological disorders, suggesting that understanding its function could provide insights into the molecular mechanisms underlying these conditions. Furthermore, exploring RAB3IL as a recombinant protein opens avenues for structural studies and the development of potential therapeutic strategies aimed at modulating its activity in pathological contexts. Consequently, research into the biochemical properties and functional roles of RAB3IL is essential for deciphering its contributions to cellular communication in the nervous system, and may pave the way for novel interventions in related diseases.

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