Analytical Data
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Gene name
RAB3B
- Application
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Alternative Names
RAB3B;Ras-related Protein Rab-3B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P20337
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Expression Region
1-219aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MASVTDGKTG VKDASDQNFD YMFKLLIIGN SSVGKTSFLF RYADDTFTPA FVSTVGIDFK VKTVYRHEKR VKLQIWDTAG QERYRTITTA YYRGAMGFIL MYDITNEESF NAVQDWATQI KTYSWDNAQV ILVGNKCDME EERVVPTEKG QLLAEQLGFD FFEASAKENI SVRQAFERLV DAICDKMSDS LDTDPSMLGS SKNTRLSDTP PLLQQNCSC
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Molecular Weight
27 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB3B is a member of the RAB family of GTPases, which play crucial roles in intracellular vesicular trafficking, particularly in synaptic transmission and neurotransmitter release in neuronal cells. The study of RAB3B has garnered significant interest due to its involvement in essential cellular processes such as exocytosis and endocytosis. Abnormalities in RAB3B function have been linked to various neurological disorders, highlighting its potential as a therapeutic target. Recombination protein technology enables the production of RAB3B in a purified form, facilitating detailed studies of its structure, function, and interactions with effectors and regulators. This research is vital for understanding the molecular mechanisms underlying RAB3B's role in synaptic activity and may provide insights into the development of drugs aimed at addressing related neurological conditions. Overall, the exploration of RAB3B recombinant proteins is a critical step in elucidating the complex pathways of membrane trafficking and their implications in health and disease.
