Analytical Data
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Gene name
RAB32
- Application
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Alternative Names
RAB32;Ras-related Protein Rab-32
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13637
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Expression Region
1-225aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHMGSHMAGGGAGDPGLGAAAAPAPETREHLF KVLVIGELGVGKTSIIKR YVHQLFSQHYRATIGVDFALKVLNWDSRTL VRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLK WKS DLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFE TSAKDNINIEEAARFLVEKILV NHQSFPNEENDVDKIKLDQETLRAEN KSQCC
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Molecular Weight
28 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB32 is a member of the RAB family of small GTPases, which are critical regulators of intracellular trafficking and membrane dynamics. This protein has garnered attention due to its involvement in various cellular processes, including organelle biogenesis, mitochondrial dynamics, and autophagy. Recent studies have highlighted RAB32's role in the regulation of melanosome transport in melanocytes, suggesting its importance in pigmentation and skin physiology. Furthermore, dysregulation of RAB32 has been implicated in several pathological conditions, including cancer and neurodegenerative diseases. Researchers have been focusing on characterizing RAB32 through recombinant protein technology to elucidate its specific functions and interactions within the cell. The generation of RAB32 recombinant proteins allows for advanced biophysical and biochemical analyses, facilitating the understanding of its mechanism of action in cellular trafficking. As such, RAB32 represents a promising target for therapeutic intervention in diseases where intracellular transport is disrupted. Understanding RAB32's function may provide insights into the development of novel strategies for the treatment of related disorders, making it a topic of significant interest in cell biology and medical research.
