Analytical Data
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Gene name
HIPK4
- Application
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Alternative Names
HIPK4；Homeodomain-interacting Protein kinase 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NE63
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Expression Region
1-616aa
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AA Sequence
MSTIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRNR IIKNELKLLHCMRGLDPEEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQ KENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLKPENIMLVDQTRC PFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWS LGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAACKAHHFFK RNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVA SRLTFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVS MQQLRSAHETTHYYQLSLRSYRLSLQVEGKPPTPVVAAEDGTPYYCLAEE KEAAGMGSVAGSSPFFREEKAPGMQRAIDQLDDLSLQEAGHGLWGETCTN AVSDMMVPLKAAITGHHVPDSGPEPILAFYSSRLAGRHKARKPPAGSKSD SNFSNLIRLSQVSPEDDRPCRGSSWEEGEHLGASAEPLAILQRDEDGPNI DNMTMEAERPDPELFDPSSCPGEWLSEPDCTLESVRGPRAQGLPPRRSHQ HGPPRGATSFLQHVTGHH
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Molecular Weight
85 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HIPK4 (Homeodomain Interacting Protein Kinase 4) is a serine/threonine kinase that belongs to the homeodomain interacting protein kinase family, which plays a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. This protein has gained attention in recent years due to its involvement in several biological pathways and its potential implications in cancer and other diseases. Research indicates that HIPK4 may interact with transcription factors and modulate their activity, thereby influencing gene expression and cellular responses. Additionally, studies have shown that aberrant regulation of HIPK4 can lead to tumorigenesis and affect the progression of certain cancers. To better understand its biological functions and therapeutic potential, scientists have focused on producing recombinant HIPK4 protein. This recombinant protein can be utilized for biochemical assays, structural studies, and functional analyses, aiding in the identification of its substrates and binding partners. Moreover, investigating the dynamics of HIPK4 in cellular contexts may reveal novel insights into its role in disease mechanisms and provide a foundation for the development of targeted therapies. As the field advances, elucidating the specific functions and regulatory mechanisms of HIPK4 will be essential for harnessing its potential in clinical applications.
