Analytical Data
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基因名
MTMR11
- Application
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别名
MTMR11; Myotubularin-related protein 11; Cisplatin resistance-associated protein; hCRA; Inactive phosphatidylinositol 3-phosphatase 11
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A4FU01
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表达区间
1-709 aa
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氨基酸序列
MWWGGRGQSF NIAPQKEEPE MGSVQENRMP EPRSRQPSSC LASRCLPGEQ ILAWAPGVRK GLEPELSGTL ICTNFRVTFQ PCGWQWNQDT PLNSEYDFAL VNIGRLEAVS GLSRVQLLRP GSLHKFIPEE ILIHGRDFRL LRVGFEAGGL EPQAFQVTMA IVQARAQSNQ AQQYSGITLS KAGQGSGSRK PPIPLMETAE DWETERKKQA ARGWRVSTVN ERFDVATSLP RYFWVPNRIL DSEVRRAFGH FHQGRGPRLS WHHPGGSDLL RCGGFYTASD PNKEDIRAVE LMLQAGHSDV VLVDTMDELP SLADVQLAHL RLRALCLPDS SVAEDKWLSA LEGTRWLDYV RACLRKASDI SVLVTSRVRS VILQERGDRD LNGLLSSLVQ LLSAPEARTL FGFQSLVQRE WVAAGHPFLT RLGGTGASEE APVFLLFLDC VWQLLQQFPA DFEFSEFFLL ALHDSVRVPD TLTFLRNTPW ERGKQSGQLN SYTQVYTPGY SQPPAGNSFN LQLSVWDWDL RYSNAQILQF QNPGYDPEHC PDSWLPRPQP SFMVPGPPSS VWLFSRGALT PLNQLCPWRD SPSLLAVSSR WLPRPAISSE SLADQEWGLP SHWGACPLPP GLLLPGYLGP QIRLWRRCYL RGRPEVQMGL SAPTISGLQD ELSHLQELLR KWTPRISPED HSKKRDPHTI LNPTEIAGIL KGRAEGDLG
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分子量
79.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
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Protein Description
MTMR11 (Myotubularin-related protein 11) is a member of the myotubularin family of proteins, which are implicated in cellular processes such as phosphoinositide metabolism, membrane trafficking, and cytoskeletal organization. Research on MTMR11 has gained significance due to its association with various cellular functions and potential links to certain diseases, particularly those affecting muscle and nerve function. Understanding the structural and functional properties of MTMR11 is crucial for elucidating its role in cellular signaling pathways and identifying how its dysregulation may contribute to pathological conditions. The study of MTMR11 recombinant proteins allows for detailed investigation into their enzymatic activity, interaction with substrates, and potential therapeutic applications. Furthermore, achieving the recombination and purification of MTMR11 facilitates advanced research techniques, such as structural biology and functional assays, which are essential for deciphering the molecular mechanisms underlying MTMR11's involvement in cellular processes. As conditions like Charcot-Marie-Tooth disease and other neuromuscular disorders are linked to mutations in myotubularin-related proteins, establishing the biochemical characteristics of MTMR11 could pave the way for novel diagnostic and therapeutic strategies, thereby enhancing our understanding of these complex diseases.
