Analytical Data
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基因名
RAB10
- Application
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别名
RAB10;Ras-related Protein Rab-10
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P61026
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表达区间
1-200aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MAKKTYDLLF KLLLIGDSGV GKTCVLFRFS DDAFNTTFIS TIGIDFKIKT VELQGKKIKL QIWDTAGQER FHTITTSYYR GAMGIMLVYD ITNGKSFENI SKWLRNIDEH ANEDVERMLL GNKCDMDDKR VVPKGKGEQI AREHGIRFFE TSAKANINIE KAFLTLAEDI LRKTPVKEPN SENVDISSGG GVTGWKSKCC
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分子量
25 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB10, a member of the RAB family of small GTPases, plays a crucial role in intracellular transport processes, particularly in the regulation of membrane trafficking and organelle dynamics. As a key player in endosomal and vesicular transport, RAB10 has been implicated in various cellular functions, including nutrient uptake, cellular signaling, and exocytosis. Recent studies have highlighted the significance of RAB10 in several physiological and pathological contexts, particularly in the development of neurodegenerative diseases and cancers. Research has focused on its role in the regulation of insulin secretion in pancreatic beta cells and its involvement in the transport of glucose transporter proteins, demonstrating its vital contribution to metabolic processes. Additionally, RAB10's interactions with various effector proteins and its regulatory mechanisms through GTP-GDP cycling are areas of active investigation. The recombinant expression and characterization of RAB10 provide essential insights into its function and regulatory pathways, advancing our understanding of its biological roles. Understanding RAB10's specific functions can offer new perspectives on therapeutic strategies targeting membrane trafficking pathways in diseases where RAB10 is implicated, highlighting its potential as a biomarker or therapeutic target. As the research progresses, elucidating the detailed molecular mechanisms and pathways associated with RAB10 will contribute significantly to our overall understanding of intracellular transport and its implications in health and disease.












