Cat: PA2000-9513

Recombinant Human MSX1 Protein,His

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Analytical Data

  • Gene name

    MSX1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    AA675338; AI324650; Homeobox 7; Homeobox protein Hox-7; Homeobox protein MSX 1; Homeobox protein MSX-1; Homeobox protein MSX1; Homeobox. msh like 1 ; Homeobox. msh-like 1; HOX 7; Hox 7.1; Hox-7; HOX7; Hox7.1; HYD 1; HYD1; msh (Drosophila) homeo box homolog 1 (formerly homeo box 7); Msh; msh homeo box 1; msh homeo box homolog 1; Msh homeobox 1; Msh homeobox 1 like protein; Msh homeobox 1-like protein; msh homeobox homolog 1 (Drosophila); msh homeobox homolog 1; MSH. Drosophila. Homolog of. 1; MSX 1; MSX1; MSX1_HUMAN; Muscle segment homeobox; Muscle segment homeobox. Drosophila. Homolog of. 1; OFC5; OTTHUMP00000115387 ; STHAG1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P28360

  • Expression Region

    1-303 aa

  • AA Sequence

    MAPAADMTSL PLGVKVEDSA FGKPAGGGAG QAPSAAAATA AAMGADEEGA KPKVSPSLLP FSVEALMADH RKPGAKESAL APSEGVQAAG GSAQPLGVPP GSLGAPDAPS SPRPLGHFSV GGLLKLPEDA LVKAESPEKP ERTPWMQSPR FSPPPARRLS PPACTLRKHK TNRKPRTPFT TAQLLALERK FRQKQYLSIA ERAEFSSSLS LTETQVKIWF QNRRAKAKRL QEAELEKLKM AAKPMLPPAA FGLSFPLGGP AAVAAAAGAS LYGASGPFQR AALPVAPVGL YTAHVGYSMY HLT

  • Molecular Weight

    31.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

MSX1 (Msh Homeobox 1) is a member of the msh (Muscle segment homeobox) gene family, which plays a significant role in various biological processes, including embryonic development and tissue differentiation. Research on MSX1 has gained prominence due to its involvement in craniofacial development and its association with congenital disorders, such as cleft lip and palate. MSX1 functions as a transcription factor, regulating gene expression critical for the formation of craniofacial structures. Studies have shown that mutations or dysregulation of MSX1 can lead to significant developmental anomalies, prompting investigations into its underlying mechanisms. The recombinant MSX1 protein is essential for these studies, allowing researchers to explore its functional properties and interactions with target genes. By producing this protein through recombinant DNA technology, scientists can analyze the effects of MSX1 on cellular processes and signaling pathways in vitro, providing insights into its role in normal and pathological development. Furthermore, understanding the molecular mechanisms of MSX1 can pave the way for potential therapeutic strategies in treating craniofacial malformations. Overall, the study of MSX1 recombinant protein serves as a vital avenue for elucidating the genetic basis of developmental disorders and advancing the field of regenerative medicine.

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