Cat: PA1000-2571

Recombinant Human PSMG2 Protein,His

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Analytical Data

  • Gene name

    PSMG2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    PSMG2;HCCA3;PAC2;TNFSF5IP1;Proteasome assembly chaperone 2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q969U7

  • Expression Region

    1-264aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMFVPCGE SAPDLAGFTL LMPAVSVGNV GQLAMDLIIS TLNMSKIGYF YTDCLVPMVG NNPYATTEGN STELSINAEV YSLPSRKLVA LQLRSIFIKY KSKPFCEKLL SWVKSSGCAR VIVLSSSHSY QRNDLQLRST PFRYLLTPSM QKSVQNKIKS LNWEEMEKSR CIPEIDDSEF CIRIPGGGIT KTLYDESCSK EIQMAVLLKF VSEGDNIPDA LGLVEYLNEW LQILKPLSDD PTVSASRWKI PSSWRLLFGS GLPPALF

  • Molecular Weight

    32 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

PSMG2, or Polypeptide Segment in Mitochondrial Genome 2, has garnered significant research interest due to its essential role in mitochondrial function and cellular metabolism. Mitochondria, often referred to as the powerhouse of the cell, are crucial for energy production through oxidative phosphorylation. PSMG2 has been implicated in various biological processes, including apoptosis, reactive oxygen species (ROS) regulation, and metabolic pathways. Mutations or dysregulation of PSMG2 have been associated with several diseases, including cancer and neurodegenerative disorders, making it a potential biomarker for disease progression and a target for therapeutic interventions. Understanding the structural and functional characteristics of PSMG2 is vital for elucidating its role in mitochondrial dynamics and cellular physiology. Recent advances in protein engineering and recombinant DNA technology have facilitated the production of PSMG2 in vitro, allowing researchers to study its interactions and effects on cellular processes. This research not only aims to pinpoint the mechanistic pathways involving PSMG2 but also seeks to explore its potential applications in drug development and gene therapy. As such, PSMG2 stands at the intersection of molecular biology and clinical research, holding promise for future advancements in the understanding and treatment of mitochondrial-related diseases.

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