Analytical Data
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Gene name
PSMD13
- Application
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Alternative Names
PSMD13;26S proteasome non-ATPase regulatory subunit 13
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UNM6
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Expression Region
1-376aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHMGSMKDVPGFLQQSQNSGPGQPAVWHRLEE LYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLV EIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGD LQVTKETIED VEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKD LPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTL YAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPAN HRQLTFEEIA KSAKITVNEV ELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWC TDVKSMEMLVEHQAHDILT
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Molecular Weight
45 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PSMD13 (Proteasome 26S Subunit, Non-ATPase 13) is a critical component of the 26S proteasome, which plays a vital role in the ubiquitin-proteasome pathway, responsible for degrading ubiquitinated proteins and regulating various cellular processes. Its involvement in the proteolytic system underscores its significance in maintaining protein homeostasis and cellular function. Research has indicated that PSMD13 may be implicated in several biological processes and diseases, including cancer, neurodegenerative disorders, and immune responses. Given its essential role, understanding the structure and function of PSMD13 is crucial for elucidating its mechanisms within the proteasome. The study of recombinant PSMD13 protein aids in characterizing its biochemical properties and interactions, thus providing insights into its role in the pathogenesis of diseases. Furthermore, recombinant PSMD13 can serve as a valuable tool for drug development, potentially leading to novel therapeutic strategies that target the proteasomal pathway. As such, the exploration of PSMD13 not only enhances our understanding of cellular physiology but also opens new avenues for biomedical research and therapeutic interventions.
