Analytical Data
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基因名
MRPL49
- Application
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别名
MRPL49; C11orf4; NOF1; OK/SW-cl.67; 39S ribosomal protein L49; mitochondrial; L49mt; MRP-L49; Mitochondrial large ribosomal subunit protein mL49; Neighbor of FAU; NOF; Protein NOF1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13405
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表达区间
1-166 aa
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氨基酸序列
MAATMFRATL RGWRTGVQRG CGLRLLSQTQ GPPDYPRFVE SVDEYQFVER LLPATRIPDP PKHEHYPTPS GWQPPRDPPP NLPYFVRRSR MHNIPVYKDI THGNRQMTVI RKVEGDIWAL QKDVEDFLSP LLGKTPVTQV NEVTGTLRIK GYFDQELKAW LLEKGF
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分子量
19.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL49, or Mitochondrial Ribosomal Protein L49, is a crucial component of the mitochondrial ribosome, playing a significant role in mitochondrial protein synthesis, which is essential for organelle function and cellular energy production. Recent studies have highlighted the importance of mitochondrial ribosomal proteins in various diseases, including mitochondrial disorders and age-related degenerative conditions. Research on MRPL49 has gained momentum due to its potential implications in understanding mitochondrial dysfunction, oxidative stress, and the regulation of apoptosis. Notably, alterations in MRPL49 expression levels have been associated with certain cancers, indicating its role as a potential biomarker and therapeutic target. Thus, the investigation of MRPL49 recombinant protein offers valuable insights into its structure-function relationship, interactive pathways, and the development of targeted therapies. This research can pave the way for novel interventions in mitochondrial diseases and contribute to a broader understanding of mitochondrial biology and its impact on human health. The generation of MRPL49 recombinant protein enables detailed functional assays and structural characterization, facilitating exploration of its role in ribosome assembly and translational regulation.
