Analytical Data
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基因名
MRPL44
- Application
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别名
MRPL44; 39S ribosomal protein L44; mitochondrial; L44mt; MRP-L44; EC 3.1.26.-; Mitochondrial large ribosomal subunit protein mL44
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H9J2
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表达区间
31-332 aa
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氨基酸序列
VKKGFRAAFR FQKELERQRL LRCPPPPVRR SEKPNWDYHA EIQAFGHRLQ ENFSLDLLKT AFVNSCYIKS EEAKRQQLGI EKEAVLLNLK SNQELSEQGT SFSQTCLTQF LEDEYPDMPT EGIKNLVDFL TGEEVVCHVA RNLAVEQLTL SEEFPVPPAV LQQTFFAVIG ALLQSSGPER TALFIRDFLI TQMTGKELFE MWKIINPMGL LVEELKKRNV SAPESRLTRQ SGGTTALPLY FVGLYCDKKL IAEGPGETVL VAEEEAARVA LRKLYGFTEN RRPWNYSKPK ETLRAEKSIT AS
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分子量
37.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL44, a key mitochondrial ribosomal protein, plays a crucial role in the protein synthesis within mitochondria, influencing cellular energy metabolism and mitochondrial function. Research has shown that MRPL44 is involved in the assembly of mitochondrial ribosomes, which are essential for translating mitochondrial genes encoded by mitochondrial DNA. Dysregulation of MRPL44 expression has been linked to various mitochondrial diseases and disorders associated with impaired oxidative phosphorylation, highlighting its importance in maintaining cellular homeostasis. Studies have also suggested that MRPL44 interacts with other mitochondrial proteins and pathways, indicating its potential role in broader metabolic processes and cellular responses to stress. As the understanding of MRPL44's functions evolves, there is increasing interest in its potential therapeutic implications, particularly in the context of diseases caused by mitochondrial dysfunction. The investigation of MRPL44 recombinant proteins has become an essential aspect of research aimed at elucidating the molecular mechanisms underlying mitochondrial biology and exploring the development of novel therapeutic strategies to address mitochondrial-related diseases. By employing advanced molecular biology techniques, researchers aim to characterize MRPL44 protein interactions and functional biochemistry, paving the way for future insights into mitochondrial dynamics and their implications in human health.
