Analytical Data
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Gene name
CRMP5
- Application
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Alternative Names
CRMP5；CRMP5；ULIP6；Dihydropyrimidinase-related Protein 5
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BPU6
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Expression Region
1-564aa
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AA Sequence
MLANSASVRILIKGDKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKV IDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGH VLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVR EKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAE GAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSS ISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPL RLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSG VQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADA DVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENG VFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRGVDRTPYLGDVAVVV HPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPERASA RILAPPGGRSSGIW
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Molecular Weight
88 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CRMP-5 (Collapsin Response Mediator Protein 5) is a crucial intracellular signaling protein that plays a significant role in neuronal development, synaptic plasticity, and the regulation of axon growth and guidance. Given its involvement in neurodevelopmental processes, CRMP-5 has garnered interest in both basic neuroscience and clinical research. Dysregulation of this protein has been implicated in various neurological disorders, including schizophrenia, where abnormal CRMP-5 expression levels are observed, and in neurodegenerative diseases like Alzheimer's disease, where it may affect neuronal survival and functionality. The study of CRMP-5 as a recombinant protein offers valuable insights into its functional mechanisms and potential therapeutic targets. By producing CRMP-5 in a recombinant form, researchers can investigate its structural characteristics, interaction with other cellular proteins, and its role in signaling pathways. This enables the exploration of its potential as a biomarker for neurological diseases and a target for drug development. Furthermore, understanding the molecular interactions and pathways involving CRMP-5 could lead to advancements in therapeutic strategies aimed at modulating its activity for the treatment of various neurological conditions. Overall, the research into CRMP-5 recombinant protein is not only pivotal for elucidating fundamental neurological processes but also holds promise for innovative therapeutic approaches in neurobiology.
