Analytical Data
-
基因名
MRPL35
- Application
-
别名
MRPL35; BM-007; 39S ribosomal protein L35; mitochondrial; L35mt; MRP-L35; Mitochondrial large ribosomal subunit protein bL35m
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9NZE8
-
表达区间
1-188 aa
-
氨基酸序列
MAASAFAGAVRAASGILRPLNILASSTYRNCVKNASLISALSTGRFSHIQTPVVSSTPRLTTSERNLTCGHTSVILNRMAPVLPSVLKLPVRSLTYFSARKGKRKTVKAVIDRFLRLHCGLWVRRKAGYKKKLWKKTPARKKRLREFVFCNKTQSKLLDKMTTSFWKRRNWYVDDPYQKYHDRTNLKV
-
分子量
47.9 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRPL35, or Mitochondrial Ribosomal Protein L35, is a crucial component of the mitochondrial ribosome, playing a significant role in mitochondrial protein synthesis. Recent studies have highlighted the importance of MRPL35 in maintaining mitochondrial function and overall cellular health. As mitochondria are essential for ATP production and metabolic processes, understanding the function of MRPL35 could provide insights into various mitochondrial-related diseases, including neurodegenerative disorders and metabolic syndromes. Research has shown that alterations in MRPL35 expression or function can lead to defects in mitochondrial translation, ultimately impacting cellular energy metabolism and contributing to the pathogenesis of certain diseases. Furthermore, MRPL35 is also associated with the regulation of the mitochondrial unfolded protein response, linking it to stress response pathways within cells. Investigating the structure and function of MRPL35, along with its interactions with other mitochondrial ribosomal proteins, can unveil potential therapeutic targets for treating mitochondrial dysfunctions. By employing techniques such as recombinant protein expression and purification, researchers aim to elucidate the precise role of MRPL35 in mitochondrial biology and its implications in human health and disease. Ultimately, this research could pave the way for developing innovative strategies to combat mitochondrial diseases by targeting the molecular mechanisms associated with MRPL35.
