Analytical Data
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基因名
PSG1
- Application
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别名
PSG1;B1G1;PSBG1;PSGGA;Pregnancy-specific beta-1-glycoProtein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P11464
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表达区间
35-426aa
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氨基酸序列
QVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRDLYHYITSYVV DGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGV TGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNG QSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLN LLPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSP RVRRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDL PRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQKLFIRHI TTKHSGLYVCSVRNSATGKESSKSMTVEVSGKWIPASLAIGF
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分子量
69 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PSG1, or Placental-Specific Gene 1, is a member of the PSG gene family known for its expression in the placenta and its association with various physiological roles during pregnancy. The gene is primarily studied for its potential immunomodulatory functions, as it appears to play a significant role in modulating maternal immune responses to ensure fetal tolerance. Research suggests that PSG1 may influence the behavior of immune cells, such as macrophages and T cells, which is crucial for maintaining the delicate balance between the maternal and fetal immune systems. Additionally, PSG1 has been implicated in various pathological conditions, including pregnancy-related complications and certain cancers, making it a protein of interest for further investigation. Its unique expression profile and potential therapeutic implications have prompted studies focused on elucidating its structure, function, and mechanisms of action. Understanding PSG1 at a molecular level can contribute to the development of novel diagnostic and therapeutic strategies for pregnancy-related issues, as well as broader applications in immune regulation and cancer therapy. Overall, PSG1 represents a compelling target for research within both reproductive biology and immunology, highlighting the intricate connections between immune function and reproductive health.
