Analytical Data
-
Gene name
MRPL34
- Application
-
Alternative Names
MRPL34; 39S ribosomal protein L34; mitochondrial; L34mt; MRP-L34; Mitochondrial large ribosomal subunit protein bL34m
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9BQ48
-
Expression Region
1-92 aa
-
AA Sequence
MAVLAGSLLGPTSRSAALLGGRWLQPRAWLGFPDAWGLPTPQQARGKARGNEYQPSNIKRKNKHGWVRRLSTPAGVQVILRRMLKGRKSLSH
-
Molecular Weight
36.6 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRPL34, a gene encoding a mitochondrial ribosomal protein, plays a significant role in the synthesis of mitochondrial proteins, which are essential for cellular respiration and energy production. Research into MRPL34 is particularly relevant due to its involvement in mitochondrial function and its potential implications in various diseases, including mitochondrial myopathies and metabolic disorders. As mitochondrial dysfunction is increasingly recognized as a contributing factor in a range of pathologies, understanding the role of MRPL34 can provide insights into the molecular mechanisms driving these conditions. Recent studies have suggested that mutations or alterations in MRPL34 can disrupt mitochondrial translation and lead to impaired energy metabolism, further highlighting its importance in maintaining cellular homeostasis. Additionally, exploring the structure and function of MRPL34 may aid in identifying therapeutic targets for conditions associated with mitochondrial dysfunction. Therefore, MRPL34 serves as a critical focus in mitochondrial biology, with implications for both basic research and clinical applications aimed at addressing mitochondrial-related diseases.
