Analytical Data
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基因名
MRPL30
- Application
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别名
MRPL30; MRPL28; RPML28; HSPC249; 39S ribosomal protein L30; mitochondrial; L30mt; MRP-L30; 39S ribosomal protein L28; mitochondrial; L28mt; MRP-L28; Mitochondrial large ribosomal subunit protein uL30m
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TCC3
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表达区间
35-161 aa
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氨基酸序列
KFTRSR IPEKVFQASP EDHEKYGGDP QNPHKLHIVT RIKSTRRRPY WEKDIIKMLG LEKAHTPQVH KNIPSVNAKL KVVKHLIRIK PLKLPQGLPA EENMSNTCLK STGELVVQWH LKPVEQKAHE S
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分子量
18.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL30, or mitochondrial ribosomal protein L30, is a crucial component of the mitochondrial ribosome, playing a significant role in protein synthesis within mitochondria. Its involvement in decoding mitochondrial mRNA and facilitating the assembly of mitochondrial ribosomes underscores its importance in maintaining mitochondrial function and cellular energy metabolism. Research into MRPL30 has emerged due to growing concerns about mitochondrial dysfunction, which is linked to a variety of diseases, including neurodegenerative disorders, metabolic syndromes, and certain cancers. The study of MRPL30 offers insights into mitochondrial biology and the potential for targeted therapeutic strategies. Understanding its structure, function, and the mechanisms by which it contributes to mitochondrial ribosome assembly can shed light on the pathophysiology of diseases associated with mitochondrial malfunction. Advances in techniques such as X-ray crystallography and cryo-electron microscopy have provided valuable structural information, allowing researchers to explore the functional implications of MRPL30 mutations and their impact on mitochondrial translation. Moreover, investigating MRPL30 in the context of mitochondrial dynamics and interaction with other mitochondrial proteins is essential for painting a comprehensive picture of mitochondrial health. As research continues to unravel the complexities of MRPL30, its significance as a potential biomarker or therapeutic target in mitochondrial-related diseases is increasingly recognized, highlighting the necessity for further investigation in this promising area of study.












