Analytical Data
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基因名
MRPL27
- Application
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别名
MRPL27; HSPC250; 39S ribosomal protein L27; mitochondrial; L27mt; MRP-L27; Mitochondrial large ribosomal subunit protein bL27m
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9P0M9
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表达区间
1-148 aa
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氨基酸序列
MASVVLALRT RTAVTSLLSP TPATALAVRY ASKKSGGSSK NLGGKSSGRR QGIKKMEGHY VHAGNIIATQ RHFRWHPGAH VGVGKNKCLY ALEEGIVRYT KEVYVPHPRN TEAVDLITRL PKGAVLYKTF VHVVPAKPEG TFKLVAML
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分子量
16.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL27, a mitochondrially encoded ribosomal protein, plays a critical role in mitochondrial protein synthesis and cellular metabolism. Research on MRPL27 has gained traction due to its involvement in various cellular processes linked to mitochondrial function, which is pivotal for energy production and cellular homeostasis. Dysregulation of mitochondrial proteins, including MRPL27, is associated with a range of diseases, particularly those related to mitochondrial dysfunction such as neurodegenerative diseases and metabolic disorders. The study of MRPL27 is essential for understanding the intricacies of mitochondrial translation, as it forms part of the mitochondrial ribosome responsible for synthesizing proteins vital for mitochondria's energy-generating functions. Moreover, exploring the functional aspects of MRPL27 can shed light on its potential role as a biomarker or therapeutic target in mitochondrial diseases. Recent advancements in molecular biology techniques have enabled researchers to investigate the structure, function, and interactions of MRPL27, providing insights into how alterations in its expression or activity might contribute to disease pathogenesis. This research is crucial for developing strategies aimed at restoring normal mitochondrial function and identifying novel therapeutic avenues for patients suffering from mitochondrial-related conditions. Thus, MRPL27 represents a significant focus of study within the broader field of mitochondrial biology and its implications in health and disease.
