Analytical Data
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基因名
MRPL14
- Application
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别名
1110006I11Rik; 39S ribosomal protein L14; 39S ribosomal protein L14 mitochondrial; 39S ribosomal protein L32; AI846816; L14mt; L32mt; mitochondrial; MRP L14; MRP L32; MRP-L14; MRP-L32; mrpl14; RM14_HUMAN
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6P1L8
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表达区间
31-145 aa
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氨基酸序列
AIQKMTRVRV VDNSALGNSP YHRAPRCIHV YKKNGVGKVG DQILLAIKGQ KKKALIVGHC MPGPRMTPRF DSNNVVLIED NGNPVGTRIK TPIPTSLRKR EGEYSKVLAI AQNFV
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分子量
15.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRPL14, or Mitochondrial Ribosomal Protein L14, is a vital component of the mitochondrial ribosome, playing a crucial role in protein synthesis within the mitochondria. Dysfunction of MRPL14 has been associated with various mitochondrial diseases, which can lead to severe metabolic disorders and mitochondrial dysfunction. Given that mitochondria are essential for cellular energy production and play significant roles in apoptosis and other cellular processes, understanding the function and structure of MRPL14 is paramount for elucidating its role in health and disease. Recent advances in molecular biology and recombinant protein technology have enabled the production of MRPL14 as a recombinant protein, facilitating the examination of its biochemical properties and interaction with other mitochondrial components. Research into MRPL14 also holds potential for therapeutic avenues, as targeting mitochondrial dysfunction is a promising strategy for treating diseases linked to mitochondrial anomalies. By studying MRPL14 in detail, researchers aim to uncover insights into mitochondrial biogenesis, regulation, and the implications of its dysfunction, ultimately contributing to the broader understanding of mitochondrial pathophysiology and potential intervention strategies.












