Analytical Data
-
基因名
CIS3
- Application
-
别名
CIS3;C1orf7;CIAS1;NALP3;NACHT. LRR and PYD domains-containing Protein 3
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P47001
-
表达区间
65-227aa
-
氨基酸序列
DVISQIGDGQVQATSAATAQATDSQAQATTTATPTSSEKISSSASKTSTNATSSSCATPSLKDSSCKNSGTLELTLKDGVLTDAKGRIGSIVANRQFQFDGPPPQAGAIYAAGWSITEDGYLALGDSDVFYQCLSGNFYNLYDQNVAEQCSAIHLEAVSLVDC
-
分子量
24.3 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CIS3, or cytokine-inducible SH2-containing protein 3, is a member of the CIS family of proteins that play critical roles in cellular signaling pathways, particularly in response to cytokines and growth factors. Researchers have been increasingly focused on CIS3 due to its involvement in regulating immune responses, hematopoiesis, and various signaling cascades related to cell proliferation and differentiation. The understanding of CIS3 has gained momentum with advances in molecular biology techniques, which have facilitated the study of its structure, function, and interactions with other signaling molecules. Significant interest in CIS3 arises from its potential implications in diseases such as cancer, autoimmune disorders, and inflammatory conditions, where dysregulation of cytokine signaling often contributes to pathogenesis. By investigating CIS3 recombinant proteins, scientists aim to unravel its precise mechanisms of action, explore its role in disease processes, and identify potential therapeutic targets. The development of recombinant forms of CIS3 allows for high-throughput studies and the possibility of designing novel cytokine-based therapeutics, which could lead to innovative treatment strategies for various conditions associated with cytokine signaling imbalances. Overall, the research on CIS3 recombinant proteins reflects a broader interest in cytokine signaling networks and their physiological and pathological implications in health and disease.












