Analytical Data
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Gene name
PROCR
- Application
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Alternative Names
PROCR;EPCR;Endothelial Protein C receptor
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UNN8
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Expression Region
18-210aa
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AA Sequence
SQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTS
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Molecular Weight
26.0kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PROCR, or Protein C Receptor, is a cellular receptor that plays a crucial role in the regulation of coagulation and inflammation processes within the body. It is known to bind to activated protein C (aPC), leading to a variety of biological effects that influence vascular integrity and promote anti-inflammatory responses. Research on PROCR has gained significant interest due to its implications in various pathological conditions, including cardiovascular diseases, sepsis, and autoimmune disorders. The ability of PROCR to modulate the activation of protein C enhances our understanding of hemostasis and the inflammatory response. Moreover, the manipulation of PROCR pathways offers potential therapeutic avenues for treating conditions linked with dysregulated coagulation and inflammation. Recent studies have focused on the structural biology and functional mechanisms of PROCR, paving the way for the development of recombinant PROCR proteins. These recombinant proteins hold promise for being used in clinical applications as novel therapeutic agents. Investigating the intricacies of PROCR function not only elucidates its role in normal physiology but also contributes to the broader field of research aimed at creating targeted treatments for various diseases associated with thrombosis and inflammation.
