Cat: PA2000-5196

Recombinant Human Scamp4 Protein,His

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Analytical Data

  • 基因名

    Scamp4

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Scamp4;Secretory carrier-associated membrane Protein 4

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9JKV5

  • 表达区间

    1-230aa

  • 氨基酸序列

    MAGKENNFPPLPPFLPLKPCFYQDFSDEIPVEHQVLVKRIYRLWMFYCATLGVNLVACLAWWIAGGAGANFGLALLWLVLFTPCSYVCWFRPAYKAFRADSSFNFMTFFFIFGAQFVLTVIQAIGFSGWGACGWLAAVGFFGTSVGAAVVMLVPAILFSLSALVMAVTIVKVHRIYRGAGGSLQKAQTEWSAGTWRNPPSREAQFNSFSGNSLPEYPTVPSYSSSGGHWP

  • 分子量

    26.9 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Scamp4 (Secretory Carrier Membrane Protein 4) is a member of the SCAMP protein family, which plays a critical role in intracellular membrane trafficking and endosomal recycling processes. Research on Scamp4 is particularly important due to its involvement in regulating synaptic vesicle dynamics, making it a key player in neuronal communication. Previous studies have highlighted that Scamp proteins, including Scamp4, contribute to the docking and fusion of vesicles with the plasma membrane, facilitating neurotransmitter release and synaptic plasticity, which are essential for learning and memory. Furthermore, alterations in Scamp4 expression or function have been implicated in various neurological disorders, underscoring the relevance of understanding its molecular mechanisms. The recombinant expression of Scamp4 allows for detailed biochemical and biophysical characterization, enabling researchers to explore its structure-function relationships, interactions with other proteins, and its regulatory role in endosomal recycling pathways. This knowledge is crucial in deciphering the complexities of synaptic transmission and could potentially lead to therapeutic strategies for treating cognitive disorders linked to synaptic dysfunction. In summary, studying Scamp4 through recombinant protein techniques provides valuable insights into cellular mechanisms essential for proper neuronal function and holds promise for future research in neurobiology and related therapeutic developments.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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