Analytical Data
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Gene name
PPP1R11
- Application
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Alternative Names
PPP1R11;HCGV;TCTE5;E3 ubiquitin-Protein ligase PPP1R11
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60927
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Expression Region
1-126aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAEAGAG LSETVTETTV TVTTEPENRS LTIKLRKRKP EKKVEWTSDT VDNEHMGRRS SKCCCIYEKP RAFGESSTES DEEEEEGCGH THCVRGHRKG RRRATLGPTP TTPPQPPDPS QPPPGPMQH
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Molecular Weight
16 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PPP1R11, also known as Protein Phosphatase 1 Regulatory Subunit 11, plays a crucial role in the regulation of protein phosphatase 1 (PP1), an enzyme involved in numerous cellular processes including cell division, muscle contraction, and synaptic plasticity. Recent studies have highlighted the significance of PPP1R11 in modulating the activity of PP1 through its interaction with various cellular signaling pathways. Dysregulation of PPP1R11 has been implicated in several diseases, including cancer and neurological disorders, making it a potential therapeutic target. The research surrounding recombinant PPP1R11 involves the expression and purification of this protein to elucidate its functional mechanisms and interaction with PP1. Understanding how PPP1R11 regulates PP1 activity may provide insights into the development of novel treatments for conditions associated with PP1 dysregulation. Therefore, investigating the properties and functions of recombinant PPP1R11 is essential for advancing our knowledge of cellular signaling and its implications in health and disease.
