Analytical Data
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Gene name
C1qtnf6
- Application
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Alternative Names
C1qtnf6；CTRP6；Complement C1q tumor necrosis factor-related Protein 6
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6IR41
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Expression Region
25-264aa
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AA Sequence
VPTEETTFGESVASHLPKGCRRCCDPEDLMSSDDTVQAPVSPYVLPEVRPYINITILKGDKGDRGPTGTPGKPGKNGTRGDRGSQGVKGDKGQAGSPGSSCQTHYSAFSVGRKTGLHSSENFLSLLFDRVFVNTDGHFDMATGSFVAPLRGLYFFSLNVHSWNYKETYVHIVHNEQAVVILYAQPSERSIMQSQSVMLPLVPGDRVWVRLFKRERENGIYSDDVDTYITFSGHLIKAEDN
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Molecular Weight
39.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C1qtnf6, a member of the complement component C1q family, has gained interest in recent years due to its potential roles in various biological processes, including immunomodulation, cell signaling, and the regulation of adipocyte function. Originally identified for its involvement in the complement system, emerging studies suggest that C1qtnf6 might play significant roles in metabolism and inflammation, linking it to conditions such as obesity and metabolic syndrome. Its expression is notably influenced by factors such as adipocyte differentiation and inflammatory cytokines, indicating a complex regulatory mechanism. Researchers are exploring C1qtnf6’s influence on insulin sensitivity, lipid metabolism, and the inflammatory response, which may pave the way for novel therapeutic targets for metabolic disorders. Understanding the functional implications of C1qtnf6 at the molecular level could provide insights into the interplay between immune responses and metabolic health, highlighting its potential as a biomarker or therapeutic target in diseases characterized by chronic inflammation, such as type 2 diabetes and cardiovascular diseases. As the scientific community continues to investigate the diverse functions of C1qtnf6, its reconstitution and functional studies using recombinant protein may elucidate its contributions to cellular physiology and pathophysiology.
