Analytical Data
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基因名
MLF2
- Application
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别名
MLF 2; MLF2; MLF2_HUMAN; Myelodysplasia myeloid leukemia factor 2 ; Myelodysplasia-myeloid leukemia factor 2; Myeloid leukemia factor 2; NTN 4; NTN4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15773
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表达区间
1-248 aa
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氨基酸序列
MFRFMRDVEP EDPMFLMDPF AIHRQHMSRM LSGGFGYSPF LSITDGNMPG TRPASRRMQQ AGAVSPFGML GMSGGFMDMF GMMNDMIGNM EHMTAGGNCQ TFSSSTVISY SNTGDGAPKV YQETSEMRSA PGGIRETRRT VRDSDSGLEQ MSIGHHIRDR AHILQRSRNH RTGDQEERQD YINLDESEAA AFDDEWRRET SRFRQQRPLE FRRLESSGAG GRRAEGPPRL AIQGPEDSPS RQSRRYDW
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分子量
28.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MLF2 (Myeloid Leukemia Factor 2) is a transcriptional coactivator that plays a significant role in hematopoiesis and is implicated in various leukemias. MLF2 functions primarily by interacting with DNA-binding proteins to regulate gene expression, thereby influencing cell differentiation, proliferation, and survival. Research into MLF2 has gained momentum due to its potential role as a biomarker for certain types of leukemias and its involvement in the progression of hematological malignancies. Moreover, MLF2 has been associated with other cellular processes, including apoptosis and response to stress, which further underscores its importance in cancer biology. The study of MLF2 recombinant proteins is critical for elucidating the molecular mechanisms underlying its function, as well as for developing therapeutic strategies targeting MLF2-related pathways. Understanding the structure and function of MLF2 through recombinant protein studies may provide insights into novel interventions for leukemia and enhance our grasp of tumorigenesis in myeloid cells. Overall, the investigation of MLF2 and its recombinant forms holds promise for advancing the understanding of cancer mechanisms and improving treatment outcomes for patients with hematological disorders.
