Cat: PA1000-2421

Recombinant Human PLCXD3 Protein,His

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Analytical Data

  • Gene name

    PLCXD3

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    PLCXD3;PI-PLC X domain-containing Protein 3

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q63HM9

  • Expression Region

    1-321aa

  • AA Sequence

    MASSQGKNEL KLADWMATLP ESMHSIPLTN LAIPGSHDSF SFYIDEASPV GPEQPETVQN FVSVFGTVAK KLMRKWLATQ TMNFTGQLGA GIRYFDLRIS TKPRDPDNEL YFAHGLFSAK VNEGLEEINA FLTDHHKEVV FLDFNHFYGM QKYHHEKLVQ MLKDIYGNKM CPAIFAQEVS LKYLWEKDYQ VLVFYHSPVA LEVPFLWPGQ MMPAPWANTT DPEKLIQFLQ ASITERRKKG SFFISQVVLT PKASTVVKGV ASGLRETITE RALPAMMQWV RTQKPGESGI NIVTADFVEL GDFISTVIKL NYVFDEGEAN T

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

PLCXD3, a member of the phospholipase C (PLC) family, plays a crucial role in cellular signaling processes by hydrolyzing phosphatidylinositol 4,5-bisphosphate to generate inositol trisphosphate and diacylglycerol, which are key second messengers in various physiological pathways. Research into PLCXD3 has gained momentum due to its implications in several biological processes, including cell proliferation, differentiation, and apoptosis, as well as its potential association with various diseases, particularly cancer. The study of recombinant PLCXD3 protein is critical for elucidating its structure-function relationships, understanding its enzymatic mechanisms, and exploring its interactions with other cellular proteins. This knowledge could lead to the development of novel therapeutic strategies targeting PLCXD3-related pathways in diseases. Furthermore, the production of recombinant PLCXD3 facilitates the generation of specific antibodies and aids in high-throughput screening of potential inhibitors, thereby supporting drug discovery efforts. Overall, advancing research on PLCXD3 and its recombinant forms may provide significant insights into targeted therapies and contribute to a deeper understanding of cellular signaling dynamics in health and disease.

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