Analytical Data
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基因名
PHOSPHO1
- Application
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别名
PHOSPHO1;Phosphoethanolamine/phosphocholine phosphatase
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TCT1
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表达区间
1-267aa
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氨基酸序列
MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVILISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKSC
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分子量
33.7kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PHOSPHO1 is a phosphatase that plays a crucial role in skeletal mineralization and bone turnover. Its significance is underscored by its involvement in the regulatory mechanisms that govern phosphate and pyrophosphate levels in the extracellular matrix, which are essential for proper bone formation and health. The study of PHOSPHO1 recombinant protein has gained attention due to its potential implications in understanding bone-related diseases such as osteoarthritis and osteoporosis. Research suggests that dysregulation of PHOSPHO1 can lead to impaired mineralization and, consequently, abnormalities in bone development. By producing and characterizing recombinant PHOSPHO1, scientists aim to elucidate its biochemical properties, understand its interaction with other proteins, and explore its functional role in cellular processes related to bone metabolism. The recombinant protein serves as a valuable tool for in vitro studies, allowing for the investigation of its enzymatic activity and regulatory mechanisms. Furthermore, insights from PHOSPHO1 research could contribute to the development of targeted therapies for bone disorders, making it a promising focus for ongoing investigations in bone biology and mineralization.
