Analytical Data
-
基因名
PTPRZ
- Application
-
别名
PTPRZ；HTPZP2；PTPRZ；PTPRZ2；Receptor-type tyrosine-Protein phosphatase zeta
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P23471
-
表达区间
36-300aa
-
氨基酸序列
IGWSYTGALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSLENTFIHNTGKTVEINLTNDYRVSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPLEMQIYCFDADRFSSFEEAVKGKGKLRALSILFEVGTEENLDFKAIIDGVESVSRFGKQAALDPFILLNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQQSGYVMLMDYLQNNFREQQYKFSRQVFSSY
-
分子量
34.1 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PTPRZ (Protein Tyrosine Phosphatase Receptor Type Z) is a member of the receptor-type protein tyrosine phosphatases (RPTPs) family, which plays a crucial role in regulating various cellular processes, including cell growth, differentiation, and signaling pathways. Its involvement in neurodevelopment and nervous system function has garnered significant attention, particularly in the context of brain function and neurodegenerative diseases. Recent studies have indicated that PTPRZ is implicated in the regulation of neuronal glue proteins, influencing synaptic plasticity and neural repair mechanisms. Abnormal expression or function of PTPRZ has been associated with neurological disorders, such as schizophrenia and multiple sclerosis, highlighting its potential as a therapeutic target. Researchers have sought to understand the structure-activity relationship of PTPRZ through the development of recombinant proteins, allowing for in-depth analysis of its biochemical properties and signaling capabilities. These studies have shed light on the molecular mechanisms underlying its function and highlighted its role in mediating cell-cell interactions and modulating extracellular matrix components. Understanding the biological significance of PTPRZ is essential for developing innovative strategies for therapeutic interventions in neurodegenerative diseases and other disorders linked to its dysregulation.
