Analytical Data
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基因名
MEST
- Application
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别名
MEST; PEG1; Mesoderm-specific transcript homolog protein; Paternally-expressed gene 1 protein
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5EB52
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表达区间
1-335 aa
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氨基酸序列
MVRRDRLRRMREWWVQVGLLAVPLLAAYLHIPPPQLSPALHSWKSSGKFFTYKGLRIFYQDSVGVVGSPEIVVLLHGFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSDKPRPHHYSIFEQASIVEALLRHLGLQNRRINLLSHDYGDIVAQELLYRYKQNRSGRLTIKSLCLSNGGIFPETHRPLLLQKLLKDGGVLSPILTRLMNFFVFSRGLTPVFGPYTRPSESELWDMWAGIRNNDGNLVIDSLLQYINQRKKFRRRWVGALASVTIPIHFIYGPLDPVNPYPEFLELYRKTLPRSTVSILDDHISHYPQLEDPMGFLNAYMGFINSF
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分子量
65.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MEST, or mesoderm-specific transcript, is a gene that encodes a protein implicated in various biological processes, including embryonic development and tumorigenesis. First identified in the context of mouse embryos, MEST exhibits imprinted expression, meaning it is expressed in a parent-of-origin-specific manner. This characteristic has drawn attention to its potential role in growth regulation and its association with certain diseases, particularly in the context of tumors and metabolic disorders. Recent research has focused on the reconstitution of the MEST protein to understand its functional mechanisms and interactions within signaling pathways. Given that MEST is linked to insulin resistance and obesity, its study is pivotal in the exploration of metabolic syndromes and related conditions. Furthermore, as cancer research evolves, understanding MEST's involvement in cellular growth and differentiation can provide insights into novel therapeutic targets. The recombinant expression and characterization of MEST protein has opened avenues for potential applications in biotechnology and medicine, emphasizing the importance of understanding both its physiological and pathological roles in human health.
