Analytical Data
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基因名
PDGFD
- Application
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别名
PDGFD;IEGF;SCDGFB;Platelet-derived growth factor D
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9GZP0
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表达区间
250-370aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSHMSYHDR KSKVDLDRLN DDAKRYSCTP RNYSVNIREE LKLANVVFFP RCLLVQRCGG NCGCGTVNWR SCTCNSGKTV KKYHEVLQFE PGHIKRRGRA KTMALVDIQL DHHERCDCIC SSRPPR
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分子量
17 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PDGFD, or Platelet-Derived Growth Factor D, is a member of the PDGF family, which plays a crucial role in various biological processes, including cell proliferation, migration, and survival. It primarily functions in the regulation of connective tissue development and tissue repair. Understanding the mechanisms underlying PDGFD's action has become increasingly important due to its implications in fibrotic diseases, cancer, and vascular disorders. Research has shown that PDGFD is involved in mediating cellular responses via receptor activation, particularly through PDGFRβ. Additionally, it has been implicated in the mesenchymal stem cell niche and has potential therapeutic applications in regenerative medicine. The recombinant expression of PDGFD for research purposes allows scientists to investigate its functional roles in cellular dynamics and to explore its utility in the development of targeted therapies. By harnessing the power of recombinant technology, researchers aim to better understand PDGFD's contributions to both normal physiology and pathological conditions, paving the way for innovative treatment strategies that could mitigate the consequences of PDGFD dysregulation.
