Analytical Data
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基因名
EPB41L5
- Application
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别名
EPB41L5；KIAA1548；Band 4.1-like Protein 5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9HCM4
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表达区间
1-733aa
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氨基酸序列
MLSFFRRTLGRRSMRKHAEKERLREAQRAATHIPAAGDSKSIITCRVSLLDGTDVSVDLPKKAKGQELFDQIMYHLDLIESDYFGLRFMDSAQVAHWLDGTKSIKKQVKIGSPYCLHLRVKFYSSEPNNLREELTRYLFVLQLKQDILSGKLDCPFDTAVQLAAYNLQAELGDYDLAEHSPELVSEFRFVPIQTEEMELAIFEKWKEYRGQTPAQAETNYLNKAKWLEMYGVDMHVVKARDGNDYSLGLTPTGVLVFEGDTKIGLFFWPKITRLDFKKNKLTLVVVEDDDQGKEQEHTFVFRLDHPKACKHLWKCAVEHHAFFRLRGPVQKSSHRSGFIRLGSRFRYSGKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKACATKPEELSVHNNVSTQSNGSQQAWGMRSALPVSPSISSAPVPVEIENLPQSPGTDQHDRKCIPLNIDLLNSPDLLEATIGDVIGASDTMETSQALNDVNVATRLPGLGEPEVEYETLKDTSEKLKQLEMENSPLLSPRSNIDVNINSQEEVVKLTEKCLNNVIESPGLNVMRVPPDFKSNILKAQVEAVHKVTKEDSLLSHKNANVQDAATNSAVLNENNVPLPKESLETLMLITPADSGSVLKEATDELDALLASLTENLIDHTVAPQVSSTSMITPRWIVPQSGAMSNGLAGCEMLLTGKEGHGNKDGISLISPPAPFLVDAVTSSGPILAEEAVLKQKCLLTTEL
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分子量
89.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
EPB41L5 (Erythrocyte membrane protein band 41-like 5) is a member of the protein family associated with the cytoskeletal architecture of cells, particularly in red blood cells. It plays a crucial role in maintaining cell shape and structural integrity by linking the plasma membrane to the underlying cytoskeleton. The investigation of EPB41L5 has gained significance due to its implications in various cellular processes and potential roles in disease. Research has suggested that dysregulation of cytoskeletal proteins, including EPB41L5, may be involved in pathologies such as hereditary spherocytosis and other blood disorders. Moreover, the protein may also be pertinent in the context of cancer biology, where alterations in cytoskeletal dynamics can influence tumor progression and metastasis. Understanding the functional mechanisms and interactions of EPB41L5 is essential for elucidating its contributions to cell physiology and its potential as a biomarker for specific diseases. Various recombinant protein studies have been designed to characterize EPB41L5's structure and function, providing insights into its role in cellular mechanics. By employing techniques like gene cloning, expression in heterologous systems, and biochemical assays, researchers aim to unravel the molecular underpinnings of EPB41L5 and assess its significance in both normal physiology and disease contexts. This line of research not only enhances our comprehension of erythrocyte biology but may also pave the way for novel therapeutic strategies targeting cytoskeletal abnormalities associated with various pathological conditions.
