Analytical Data
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基因名
MAP3K7IP2
- Application
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别名
CHTD2; FLJ21885; KIAA0733; MAP3K7IP2; Mitogen activated protein kinase kinase kinase 7 interacting protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; OTTHUMP00000040125; TAB 2; TAB-2; Tab2; TAB2_HUMAN; TAK1 binding protein 2; TAK1-binding protein 2; TGF beta activated kinase 1/MAP3K7 binding protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NYJ8
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表达区间
401-693aa
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氨基酸序列
MRNQPTLFISTNSGASAASRNMSGQVSMGPAFIHHHPPKSRAIGNNSATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQKARMERLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSLEEMQQLRSCNRQLQIDIDCLTKEIDLFQARGPHFNPSAIHNFYDNIGFVGPVPPKPKDQRSIIKTPKTQDTEDDEGAQWNCTACTFLNHPALIRCEQCEMPRHF
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分子量
37.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MAP3K7IP2, also known as TAB2 (TAK1-binding protein 2), plays a crucial role as an adapter protein in various signaling pathways, particularly those related to the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R)-mediated responses. It is involved in the activation of mitogen-activated protein kinases (MAPKs), which are essential for cellular responses to stress, inflammation, and survival signals. Research into the recombinant protein MAP3K7IP2 is gaining prominence due to its potential implications in understanding various diseases, including cancer and autoimmune disorders. The protein’s ability to modulate signaling cascades offers insights into cellular mechanisms that can be targeted for therapeutic interventions. Moreover, studying the recombinant form of MAP3K7IP2 allows researchers to investigate its functional properties, binding affinities, and role in cellular responses in a controlled environment. This recombinant protein can serve as a valuable tool in elucidating the complexities of MAPK signaling and the underlying molecular mechanisms of diseases, ultimately aiding in the development of novel treatment strategies. As scientists continue to explore the multifaceted roles of MAP3K7IP2, its study could reveal significant opportunities for drug development and biomarker identification, reinforcing its relevance in contemporary biomedical research.
